The difficulty in predicting the boiling incipience of highly-wetting liquids has slowed the application of immersion cooling technology in the electronics industry. The present effort sheds new light on this phenomenon by examining the influence of the dynamic solid/liquid contact angle and contact angle hysteresis on the incipience superheat. The results suggest that variations in contact angle, induced by changes in the direction and magnitude of the liquid/vapor interface velocity, can substantially affect the formation of bubble embryos and may well explain the wide experimental scatter in incipience superheat values reported for highly-wetting liquids.